"The Big Bang Theory" shines a spotlight on nerd culture thanks to hilarious storylines and endearing characters that helped shape the careers of Jim Parsons, Melissa Rauch, Simon Helberg, and Kunal Nayyar, just to name a few. While the antics of Sheldon Cooper (Parsons), Howard Wolowitz (Helberg), Raj Koothrappali (Nayyar), and Leonard Hofstadter (Johnny Galecki) already offer plenty of laughs, the show would not be complete without big guest stars.

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